TIA Biologics nodes offer multiple expression systems for industrial biotechnology and biologics production ranging from microbial, yeast, insect, or mammalian cells. Applications include pharmaceutical development, diagnostics, enzymes, and biotransformation/biocatalysis.
Facilities use automated systems such as the Beacon by Berkeley Lights to accelerate identification and outgrowth of single cell-derived clones. The platform considers manufacturability endpoints through coupling with high throughput assays to screen for high producers and associated characterisation analysis to ensure lead clones meet required process and product quality attributes.
We have over a decade of experience assisting clients in translating their novel therapeutic targets into biologics that can support clinical end points, by ensuring we always focus on quality in developing and selecting a panel of lead clonal cell lines.