Clinical Trials Infrastructure

Clinical Trials Infrastructure

Australia has an infrastructure deficiency in consumer-oriented internet resources for clinical trials.   The THD project will provide new infrastructure that will enhance the Australian New Zealand Clinical Trials Registry, increasing the useability for stakeholder groups.  This will:
•    Provide mechanisms to enable trial data submitted to ethics committees, regulators and other specialist registries to be automatically exported and displayed on ANZCTR.  
•     Utilise the now available WHO International Clinical Trials Registry Platform (ICTRP) web service so trials conducted in AUS/NZ but registered on other registries can be displayed and searched for on the ANZCTR.
•    To enable users to easily identify trials for which they are eligible
•    Service a variety of consumer and clinical speciality groups who wish to display and search for ANZ clinical trials on their own websites

The THD project will provide new infrastructure that will the recently established Paediatric Trials Network Australia, (PTNA) through the adoption of the clinical trial data management system.  This will:
•    Enhance coordination of multi-site clinical trials, supporting randomisation, direct data capture at multiple sites and allowing rapid and accurate central analysis of data.
•    Reduce times for site feasibility analyses and allow efficiencies in recruitment
•    Significantly build translation research capacity, enable collaboration and would leverage existing operational investments made by individual sites participating in paediatric clinical trials.

Australia has an infrastructure deficiency in early stage clinical trial capability, which imposes a major impediment to multi-centre trials to be conducted across Australia.  The UNSW-led Australian Advanced Treatment Centre (AATC)will be an integrated clinical research and teaching facility that houses a phase I unit.  The THD project funding will support the fit out and equipping of pharmacokinetic laboratories at the AATC.  The investment will leverage considerable University and State Government funding accumulated for AATC.