Our Researchers


Lyn Griffiths

Lyn Griffiths is a molecular geneticist who has been studying the genes involved in common human disorders for nearly two decades. Her expertise is in the field of human gene mapping and focuses on identifying the genes involved in common complex disorders, including migraine, cardiovascular disease (CVD) and several types of cancer. She is also interested in the genetic basis of human memory.

Recent studies by Professor Griffiths have included genomic analysis of the genetically isolated Norfolk Island population, who are descendants of the Bounty mutineers. In this analysis, her research team identified more than 200 sites in the genome that are associated with CVD risk, confirming 12 previously identified CVD-risk sites and discovering another four potential CVD-risk genes, which have been shown to have biological roles in disease.

Professor Griffiths is also running a Phase III migraine pharmacogenetic trial of a potential migraine treatment directed towards a migraine functional mutation. This trial is investigating the use of vitamins to restore the function of a mutated methylene tetrahydrofolate reductase gene that is found in around 20% of migraine sufferers. Her laboratory also undertakes NATA accredited DNA diagnostic testing for migraine and stroke related disorders.
Professor Griffiths was a Queensland Finalist for Australian of the Year in 2005, a nominee for the Queenslander of the Year award in 2006 and has been awarded a Centenary Medal for Distinguished Service to Education and Medical Research.

Professor Griffiths has published over 240 research papers and supervised over 30 Postgraduate and 38 Honours students. She has also filed 7 patents, two of which have been licensed to Gemini Genomics. In addition, she has been a Director of the Australian Society for Medical Research, a member of the Queensland Institute of Medical Research Council for 9 years, chaired the Scientific Program Committee for the 11th International Congress of Human Genetics and currently serves as the Chair of the Qld Institutes of Health. From 1995 to 2000 and again from 2004 to 2007, she occupied the position of Head of School of Medical Science at Griffith University, Gold Coast. In 2008, Professor Griffiths took up the role of Director of the Griffith Health Institute in conjunction with the role of Dean Research (Health), and was also the Director of the Genomics Research Centre before her move to QUT where she is currently the Executive Director of the Institute for Health and Biomedical Innovation.