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New drugs for Chagas disease

Chagas disease causes significant mortality in the Latin Americas and poses a substantial health burden in that region. Monash's Australian Translational Medicinal Chemistry Facility is working on new drugs to treat this poorly managed disease.

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IMPDH as an antifungal drug target

The human pathogenic fungus Cryptococcus neoformans causes fatal fungal meningioencephalitis in immunocompromised individuals. The increasing burden of fatal opportunistic fungal infection requires the urgent development of novel therapeutics and synergistic approaches to treatments.

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Activated Dendritic Cell Marker CD83

Dendritic cells (DCs) play a critical role in the generation and regulation of immune responses. In the healthy individual these responses are directed towards pathogenic organisms and viruses, preventing or resolving infection.

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A new therapy for asthma?

Asthma accounts for about one out of every 250 deaths worldwide and has profound health-care costs in terms of emergency room visits and hospitalisations.

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